Receptors for insulin and epidermal growth factor: Relation to synthesis of DNA in cultured rabbit lens epithelium
β Scribed by Morley D. Hollenberg
- Book ID
- 115702415
- Publisher
- Elsevier Science
- Year
- 1975
- Tongue
- English
- Weight
- 646 KB
- Volume
- 171
- Category
- Article
- ISSN
- 0003-9861
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π SIMILAR VOLUMES
Primary monolayer cultures of adult rat hepatocytes were used to study the temporal interaction of epidermal growth factor (EGF) and insulin in their stimulation of DNA synthesis. The hepatocytes were cultured both under defined conditions and with serum. EGF and insulin interacted synergistically.
## Abstract The receptors for insulin and insulinβlike growth factor I (IGFβI) have in common a high sequence homology and diverse overlapping functions, (e.g., the stimulation of acute metabolic events and the induction of cell growth.). In the present study, we have compared the potential of insu