Receptors As Supramolecular Entities. Proceedings of the Biannual Capo Boi Conference, Cagliari, Italy, 7–10 June 1981

✍ Scribed by Giovanni Biggio, Erminio Costa and P. F. Spano (Eds.)

• Publisher: Pergamon Press
• Year: 1983
• Tongue: English
• Leaves: 464
• Edition: 1st
• Category: Library

✦ Synopsis

This volume offers a panoramic view of the concepts that are being elaborated to reach a better understanding of the function of the receptors for the most important neurotransmitters operative in the brain. Receptor function is studied dynamically using transducer function measurements, changes in coupling efficiency during adaptation and drug action, and measurements of kinetic parameter for the binding of primary transmitter and cotransmitters to specific detectors

✦ Table of Contents

Content:
ADVANCES IN THE BIOSCIENCES, Page ii
Front Matter, Page iii
Copyright, Page iv
Symposia in Neuroscience, Page v, Giovanni Biggio, Erminio Costa
PREFACE: Receptors as Supramolecular Entities, Pages vii-viii, Giovanni Biggio, Erminio Costa, G.L. Gessa, P.F. Spano
Acknowledgements, Page ix
Introduction, Page xv
Radioligand Binding Studies of Dopamine Receptors in the Central Nervous System, Pages 1-50, I. Creese, A.L. Morrow, M.W. Hamblin, S.E. Leff, D.R. Sibley
Inhibitory Coupling of Dopamine Receptors to Adenylate Cyclase in Rat Anterior Pituitary, Pages 51-59, P. Onali, J.P. Schwartz, E. Costa
Possible Functional Meaning of the Coexistence of Monoamines and Peptides in the Same Neurons. A Study on the Interactions Between Cholecystokinin-8 and Dopamine in the Brain, Pages 61-70, L.F. Agnati, K. Fuxe, K. Andersson, T. Hokfelt, L. Skirboll, F. Benfenati, N. Battistini, L. Calza
Behavioral Effects of Prolactin: The Involvement of Brain Dopamine, Pages 71-85, F. Drago, J.M. van Ree, B. Bohus, U. Scapagnini, D. de Wied
DA Autoreceptors in the Substantia Nigra: Their Involvement in the Control of Nigral DA Synthesis, Pages 87-93, A. Argiolas, M.R. Melis, F. Fadda, G.L. Gessa
Modifications of Dopamine Receptors in Rat Striatum After Chronic Administration of L-Dopa, Pages 95-101, M. Cimino, M. Lipartiti, G. Vantini, S. Algeri
D₂ Receptors Modulating Dopamine Synthesis in Striatal Synaptosomes, Pages 103-112, A.H. Tissari
Evidence Against the D₁ and D₂ Dopamine Receptor Hypothesis: Studies with Sulpiride, Pages 113-129, G.N. Woodruff, J.A. Poat, S.B. Freedman
Sulpiride and Other Benzamides as Specific Antagonists at the D² Dopamine Receptor, Pages 131-138, P.F. Spano, E. Carboni, L. Garau, M. Memo, S. Govoni, M. Trabucchi
Estrogen Modulation of Dopamine Autoreceptors, Pages 139-146, F. Bernardi, M.P. Piccardi, A. Bocchetta, G.U. Corsini
Activation of Dopaminergic Neurons by Sulpiride, Pages 147-153, G.P. Mereu
Functional Similarities Between Benzamides and Other Neuroleptics, Pages 155-170, B. Zivkovic, P. Worms, B. Scatton, J. Dedek, A. Oblin, K.G. Lloyd, G. Bartholini
Behavioral and Biochemical Effects in the Adult Rat After Prolonged Postnatal Administration of Cataleptogenic and Non-cataleptogenic Neuroleptics, Pages 171-178, V. Cuomo, R. Cagiano, I. Mocchetti, E. Coen, F. Cattabeni, G. Racagni
Biochemical Pharmacology of Dopamine Neurons Innervating the Neurointermediate Lobe of Pituitary Gland, Pages 179-185, L. Annunziato, F. Cerrito, S. Balzamo
Substituted Benzamide Drugs as Selective Agents for Distinguishing Cerebral Dopamine Receptor Sub-types, Pages 187-211, P. Jenner, C.D. Marsden
The Supramolecular Organization of Receptors for Gamma-aminobutyric Acid (GABA), Pages 213-235, E. Costa
Neurochemical Indices of GABA Utilization in the Nigro-striatal System, Pages 237-252, K. Gale, M. Casu
Role of GABAergic Mechanisms Within Cerebellar Nucleus Fastigii in the Control of Posture and in the Mechanism of Action of Benzodiazepines, Pages 253-265, A. Imperato, F. Nicoletti, B. Piacente, G. Canonico, G. Di Chiara
Age-induced Loss of the Functional Link Between Benzodiazepine and GABA Binding Sites in the Rat Retina, Pages 267-272, G. Biggio, P. Guarneri, M.G. Corda, A. Concas, M. Salis, G. Calderini, G. Toffano
Effects of Inhibitors of GABA Metabolism and Transport on GABA Output from the Cerebral Cortex, Pages 273-279, F. Moroni, A. Mulas, G. Moneti, R. Corradetti, G. Pepeu
Distribution and Circadian Variations of GABA in Hypothalamic Areas Regulating Food Intake, Pages 281-287, E. Coen, F. Cattabeni, J. Blundell
An Electroencephalographic Analysis of the Convulsant Benzodiazepine 1,3-dihydro-5-methyl-2-H-1,4-benzodiazepine-2-one (Ro 5-3663), Pages 289-293, S. Sagratella, M. Massotti
³H-diazepam Binding and Interaction Between GABA and Benzodiazepine Binding Sites in Different Brain Regions of Aged Rats, Pages 295-300, A.C. Bonetti, G. Calderini, G. Aldinio, M.A. Balzano, B. Di Perri, G. Toffano
Opiate Receptors and Their Ligands, Pages 301-319, E.J. Simon
Evidence that Serotinin Modulates Opiate Neuronal Activity in Striatum, Pages 321-328, L. Dellavedova, M. Parenti, A. Groppetti
Bestatin: A Selective and Potent Inhibitor of Enkephalin Aminopeptidase, Pages 329-333, A. Carenzi, F. Casacci, E. Morpurgo, D. Della Bella
Effect of Two Modified Met-enkephalins on the EGG and Behavior of Rats and Rabbits, Pages 335-342, F. Aloisi, A. Pezzola, A. Scotti de Carolis
Acute Tolerance to and Dependence Upon Opioid Peptides in Single Spinal, Striatal and Cortical Neurons of Rats, Pages 343-350, W. Zieglgansberger, J.P. Fry, J.T. Williams
A Potent Aphrodisiac Drug Combination: Naloxone and N-n-Propyl-Norapomorphine, Pages 351-357, F. Ferrari, G. Baggio
Histamine Receptors and Actions in Mammalian Brain, Pages 359-420, J.C. Schwartz, T.T. Quach, M. Garbarg
Effect of Adenosine and ATP on Acetylcholine Release from Brain Slices, Pages 421-425, F. Pedata, L. Beani, C. Bianchi, G. Pepeu
Noradrenaline Receptor Subtypes: Their Role in the Modulation of the Release of the Neurotransmitter, Pages 427-444, S.Z. Langer
Failure of Prolactin to Inhibit Sexual Behavior in the Male Rat, Pages 445-451, W. Fratta, P. Falaschi, L. Napoli-Farris, A. Rocco, R. D'Urso, T. Buongiorno, G.L. Gessa
Antidepressants: Effects on Adrenal Activity and Brain Glucocorticoid Binding, Pages 453-459, F.R. Patacchioli, S. Scaccianoce, E. Martucci, M. Capasso, L. Angelucci
Physiological and Pharmacological Modulation of Hypothalamic Prolactin Receptors, Pages 461-469, R. Di Carlo, G. Muccioli, E. Genazzani
Interaction Between ACTH and Beta-endorphin at the CNS Level, Pages 471-476, W. Fratta, A. Bertolini, G.L. Gessa