The present report describes the in vitro and in vivo profile of CEP-751, a novel receptor tyrosine kinase inhibitor. CEP-751 at 100 nM inhibits the receptor tyrosine kinase activity of the neurotrophin receptors trkA, trkB and trkC. CEP-751 has no effect on activity of receptors for EGF, IGF-I, ins
β¦ LIBER β¦
Receptor tyrosine kinase inhibition suppresses growth of pediatric renal tumor cells in vitro
β Scribed by Shalizeh Naraghi; Sami Khoshyomn; Joseph A DeMattia; Dennis W Vane
- Book ID
- 117826774
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- English
- Weight
- 223 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0022-3468
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
CEP-751 inhibits trk receptor tyrosine k
β
Anna Marie Camoratto; Jitesh P. Jani; Thelma S. Angeles; Anna C. Maroney; Christ
π
Article
π
1997
π
John Wiley and Sons
π
French
β 134 KB
π 1 views
177 Tyrosine kinase inhibition as a stra
β
V. MacDonald; E.B. Dickerson; N. Akhtar; J.F. Modiano; S.C. Helfand
π
Article
π
2004
π
Elsevier Science
π
English
β 149 KB
Inhibition of epidermal growth factor re
β
Kazuo Umezawa; Daiji Sugata; Katsuyuki Yamashita; Noriko Johtoh; Masabumi Shibuy
π
Article
π
1992
π
Elsevier Science
π
English
β 597 KB
Expression of receptor tyrosine kinases
π
Article
π
1994
π
Elsevier Science
π
English
β 151 KB
MAZ51, an indolinone that inhibits endot
β
Vladimir Kirkin; Wilko Thiele; Petra Baumann; Ralph Mazitschek; Katrin Rohde; Gu
π
Article
π
2004
π
John Wiley and Sons
π
French
β 400 KB
π 1 views
## Abstract We have recently described MAZ51, an indolinone that blocks the ligandβinduced autophosphorylation of VEGFRβ3, a receptor tyrosine kinase that plays a central role in the regulation of lymphangiogenesis. Here we show that MAZ51 is able to block the proliferation of VEGFRβ3βexpressing hu
Apoptosis and growth inhibition of head
β
R.A. Faust; S. Tawfic; A.T. Davis; K. Ahmed
π
Article
π
1999
π
Elsevier Science
π
English
β 339 KB