Receptor-stimulated actin polymerization requires cytoplasmic acidification in human PMNs

Inosine stimulates chemotaxis, Ca2+-tran

Inosine stimulates chemotaxis, Ca2+-transients and actin polymerization in immature human dendritic cells via a pertussis toxin-sensitive mechanism independent of adenosine receptors

✍ Marco Idzko; Elisabeth Panther; Hinrich C. Bremer; Wolfram Windisch; Stephan Sor 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 150 KB

Inosine is an endogenous purine nucleoside, which is formed by adenosine deaminidase during adenosine breakdown and is released into the extracellular space from the sympathetic nervous system or injured cells. Here, we studied the biological activity of inosine on human dendritic cells (DC), which