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Receptor-mediated pinocytosis of mannose/N-acetylglucosamine-terminated glycoproteins and lysosomal enzymes by macrophages

โœ Scribed by Stahl, Philip D.; Schlesinger, Paul H.


Book ID
122717206
Publisher
Elsevier Science
Year
1980
Tongue
English
Weight
421 KB
Volume
5
Category
Article
ISSN
0968-0004

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The role of the mannose/N-acetylglucosam
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Saccharomyces cerevisiae mannan inhibits the pinocytosis of horseradish peroxidase (HRP) by resident, thioglycollate-,proteose peptone-, and Corynebacterium parvurn-elicited macrophages from 30 to 70% when 1 mgiml HRP is used, and 65 to 87% when 250 p@ml HRP is used. In contrast, HRP uptake by J774