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Receptor-Independent 4D-QSAR Analysis of a Set of Norstatine Derived Inhibitors HIV-1 Protease.

✍ Scribed by Craig L. Senese; A. J. Hopfinger


Publisher
John Wiley and Sons
Year
2003
Weight
52 KB
Volume
34
Category
Article
ISSN
0931-7597

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The 4D-QSAR Paradigm: Application to a N
✍ Santos-Filho, Osvaldoβ€…A. ;Hopfinger, Antonβ€…J. πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 206 KB πŸ‘ 2 views

4D-QSAR analysis incorporates pharmacophore, conformational and alignment freedom into the development of 3D-QSAR models for training sets of structure-activity data by performing ensemble averaging, the fourth β„’di-mension∫. The data required to perform 4D-QSAR analysis includes a training set of co