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Receptor-dependent and -independent catabolism of low-density lipoprotein in a kindred with familial hypobetalipoproteinemia

✍ Scribed by Claude L. Malmendier; Jean-F. Lontie; Claude Delcroix; Colette Sérougne; Jacqueline Férézou; Diana M. Lee


Book ID
116030496
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
851 KB
Volume
41
Category
Article
ISSN
1532-8600

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Mutations of the low density lipoprotein (LDL) receptor in 16 Japanese kindreds with homozygous familial hypercholesterolemia (FH) were studied using an anti-LDL receptor antibody. The LDL receptor mutations in Japanese FH were heterogeneous and included defects in synthesis, post-translational proc