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Receptor characterization and regulation in intact tissue preparations Pharmacological implications

โœ Scribed by Christopher A. Shaw; Michael Wilkinson


Book ID
115784006
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
1011 KB
Volume
47
Category
Article
ISSN
0006-2952

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## Abstract The increasing number of ATPโ€ and UTPโ€sensitive membrane receptors identified by cloning represent either ligandโ€activated ion channels (P2X) or Gโ€proteinโ€coupled receptors (P2Y). Adenosine, ATP, and UTP have potential application in the management of pain, cancer, and some cardiovascul