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Receptor binding and biological effect of insulin in human adipocytes

✍ Scribed by O. Andersen; J. Gliemann; S. Gammeltoft

Publisher
Springer
Year
1977
Tongue
English
Weight
497 KB
Volume
13
Category
Article
ISSN
0012-186X

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To determine whether hyperinsulinaemia can cause insulin resistance in man and, if so, whether this occurs at a receptor or post-receptor site, nine normal volunteers were infused with insulin for 6 h at a rate (2 mU X kg-1 X min-1) which resulted in steady-state plasma insulin concentrations of 140