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Receptor binding affinity and antiproliferative activity of new antiinflammatory antedrugs: 6-methoxycarbonyl prednisolone and its derivatives

✍ Scribed by Ann S. Heiman; Deasik Hong; Henry J. Lee


Book ID
116065991
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
655 KB
Volume
59
Category
Article
ISSN
0039-128X

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Synthesis of 6-(methoxycarbonyl)predniso
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The synthesis and pharmacological evaluation of 64meth-oxycarbony1)prednisolone (11) (a 3:l mixture of 6a-isomer l l a and 6&isomer llb), Its 21-01 acetates 13a (6a-isomer) and 13b (6p- isomer), and 17,21diol acetonide 14 (a 6:l mixture of 6a-isomer 14a and 6@-isomer 14b) as local antiinflammatory s

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