𝔖 Bobbio Scriptorium
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Receptor-based model accounts for phlebotomy-induced changes in erythropoietin pharmacokinetics

✍ Scribed by Sunny Hong Chapel; Peter Veng-Pedersen; Robert L. Schmidt; John A. Widness

Book ID
114216612
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
116 KB
Volume
29
Category
Article
ISSN
0301-472X

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A valid equation for the well-stirred pe
A valid equation for the well-stirred perfusion limited physiologically based pharmacokinetic model that consistently accounts for the blood–tissue drug distribution in the organ and the corresponding valid equation for the steady state volume of distribution
✍ Leonid M. Berezhkovskiy πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 165 KB πŸ‘ 1 views

A consistent account of the assumptions of the well-stirred perfusion limited model leads to the equation for the organ tissue that does not coincide with that often presented in books and papers. The difference in pharmacokinetic profiles calculated by the valid and the commonly used equations coul