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Recent progress in the discovery of small-molecule inhibitors of the HMT EZH2 for the treatment of cancer

✍ Scribed by Verma, Sharad K; Knight, Steven D


Book ID
123614578
Publisher
Future Science
Year
2013
Tongue
English
Weight
869 KB
Volume
5
Category
Article
ISSN
1756-8919

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## Abstract PTP1B is a protein tyrosine phosphatase involved in insulin and leptin signaling and is a primary mechanism for down‐regulating both the insulin and leptin receptor signaling pathways. Animals deficient in PTP1B have improved glucose regulation and lipid profiles and are resistant to we