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Recent progress in mitochondrial DNA analysis

✍ Scribed by Kazuo Umetsu; Isao Yuasa

Book ID
104039914
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
136 KB
Volume
7
Category
Article
ISSN
1344-6223

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## Abstract The reduced form of nicotinamide adenine dinucleotide coenzyme Q reductase (complex I) activity has recently been shown to be deficient in the substantia nigra of patients dying with Parkinson's disease. This biochemical defect is identical to that produced by the neurotoxin 1‐methyl‐4‐