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Recent Progress in Diazirine-Based Photoaffinity Labeling

✍ Scribed by Makoto Hashimoto; Yasumaru Hatanaka

Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
596 KB
Volume
2008
Category
Article
ISSN
1434-193X

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✦ Synopsis

Abstract

As a result of recent developments in molecular biology, the investigation of biofunctional machinery at ligand‐accepting interfaces has become one of the challenging and important subjects in the post‐genome field. The technique of photoaffinity labeling has become increasingly appreciated as a powerful methodology for this purpose. This microreviewfocuses on the synthesis of 3‐phenyl‐3‐(trifluoromethyl)diazirine, one of the most promising photophores, and its application to biomolecules.(Β© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008)

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ChemInform Abstract: Recent Progress in
ChemInform Abstract: Recent Progress in Diazirine-Based Photoaffinity Labeling
✍ Makoto Hashimoto; Yasumaru Hatanaka πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons βš– 15 KB

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