## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v
✦ LIBER ✦
Recent Developments of Carbonic Anhydrase Inhibitors as Potential Anticancer Drugs
✍ Scribed by Thiry, Anne; Supuran, Claudiu T.; Masereel, Bernard; Dogné, Jean-Michel
- Book ID
- 115465139
- Publisher
- American Chemical Society
- Year
- 2008
- Tongue
- English
- Weight
- 576 KB
- Volume
- 51
- Category
- Article
- ISSN
- 0022-2623
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## Abstract The tumor‐associated carbonic anhydrase (CA, EC 4.2.1.1) isozyme CA IX is highly overexpressed in many cancer types via the hypoxia inducible factor‐1α (HIF‐1α) cascade. Hypoxic tumors expressing CA IX show a poor response to classical chemo‐ and radio‐therapy treatments. CA IX signific
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