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Recent advances torwards understanding redox mechanisms in the activation of nuclear factor κb

✍ Scribed by Yvonne M.W Janssen-Heininger; Matthew E Poynter; Patrick A Baeuerle

Book ID
114274377
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
523 KB
Volume
28
Category
Article
ISSN
0891-5849

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Nuclear factor-kappaB (NFKB) is a transcription factor with a pivotal role in inducing genes involved in physiological processes as well as in the response to injury and infection. A model has been proposed whereby the diverse agents that activate NFkappaB do so by increasing oxidative stress within