Recent advances of siRNA delivery by nanoparticles
โ Scribed by Yuan, Xudong; Naguib, Sandy; Wu, Zhiqian
- Book ID
- 111697306
- Publisher
- Informa plc
- Year
- 2011
- Tongue
- English
- Weight
- 734 KB
- Volume
- 8
- Category
- Article
- ISSN
- 1742-5247
No coin nor oath required. For personal study only.
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## Abstract Clinical applications of genetic therapies, including delivery of short, interfering RNAs (siRNAs) for RNA interference (RNAi), are limited due to the difficulty of delivering nucleic acids to specific cells of interest while at the same time minimizing toxicity and immunogenicity. The
## Abstract Gold nanoparticles have become widely used in scientific research due to their unique physical and chemical properties. In the last several years their use as siRNA delivery agents has been investigated. Here, progress made using gold nanoparticles for siRNA delivery is described and th