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Recent advances in the isolation and structural studies of biomacromolecules using microcolumn techniques

✍ Scribed by Milos Novotny

Publisher
John Wiley and Sons
Year
1990
Tongue
English
Weight
1000 KB
Volume
2
Category
Article
ISSN
1040-7685

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✦ Synopsis

Abstract

Microcolumn liquid chromatography and capillary electrophoresis facilitate isolation of biological macromolecules at subnanogram levels. In order to characterize structurally such small amounts of labile materials, it is essential to develop new nanoscale sample treatment approaches and highly sensitive analytical techniques for the determination of biomolecular fragments. Progress in this area is summarized, using selected examples of the amino acid, peptide, and oligonucleotide separations.

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