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Recent advances in large-scale transposon mutagenesis

โœ Scribed by Lisbeth Hamer; Todd M DeZwaan; Maria Victoria Montenegro-Chamorro; Sheryl A Frank; John E Hamer

Book ID
104414490
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
76 KB
Volume
5
Category
Article
ISSN
1367-5931

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โœฆ Synopsis

Transposons were identified as mobile genetic elements over fifty years ago and subsequently became powerful tools for molecular-genetic studies. Recently, transposon-mutagenesis strategies have been developed to identify essential and pathogenicity-related genes in pathogenic microorganisms. Also, a number of in vitro transposition systems have been used to facilitate genome sequence analysis. Finally, transposon mutagenesis of yeast and complex eukaryotes has provided valuable functional genomic information to complement genome-sequencing projects.

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