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Recent Advances in Blood-Brain Barrier Transport

✍ Scribed by Pardridge, W M

Book ID
115449494
Publisher
Annual Reviews
Year
1988
Tongue
English
Weight
580 KB
Volume
28
Category
Article
ISSN
0362-1642

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Blood–brain barrier efflux transport
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Efflux transport at the blood-brain barrier (BBB) limits the brain tissue exposure to a variety of potential therapeutic agents, including compounds that are relatively lipophilic and would be predicted to permeate the endothelial lining of the brain microvasculature. Recent advances in molecular an