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Recapitulation of Ras Oncogene Mutations in Breast Cancer

✍ Scribed by Stamatakos, Michael; Stefanaki, Charikleia; Kontzoglou, Konstantinos; Masouridi, Stavroula; Sakorafas, George; Safioleas, Michael


Book ID
120944824
Publisher
S. Karger AG
Year
2010
Tongue
English
Weight
629 KB
Volume
33
Category
Article
ISSN
0378-584X

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Ras oncogene point mutations in bladder
✍ Wood, D. P. ;Anderson, A. E. ;Fair, R. ;Chaganti, R. S. K. πŸ“‚ Article πŸ“… 1992 πŸ› Springer 🌐 English βš– 486 KB

Bladder tumors respond to cisplatin-based chemotherapy in 68% of cases, but only 30% will have a durable response. Recent studies have suggested that ras point mutations may produce cisplatin drug resistance in cell lines. To determine the role of ras point mutations in human tumors resistant to cis