## Abstract 566 stageβII melanoma patients treated at the National Cancer Institute of Milan, Italy, were analyzed to evaluate the prognosis. Among the criteria considered, four were significantly associated with survival when considered as single factors: growth pattern, levels of invasion, the nu
Recall skin-test antigens and the prognosis of stage I melanoma
β Scribed by Dr. Gerard V. Aranha; Charles F. McKhann; Richard L. Simmons; Theodor B. Grage
- Publisher
- John Wiley and Sons
- Year
- 1979
- Tongue
- English
- Weight
- 245 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0022-4790
No coin nor oath required. For personal study only.
β¦ Synopsis
Thirty-one patients with Stage I melanoma were studied with regard to their response to common skin antigens. Patients were divided into two groups, those who had surgery alone, and those who had surgery and BCG. The results were comparable. It was found that the disease-free interval was longer and the recurrence rate lower in patients who demonstrated cutaneous hypersensitivity to common antigens than in those who did not. Patients who had Clark's levels I and I1 lesions were more likely to be immunocompetent. The addition of BCG in the study did not appear to decrease the rate of recurrence, which seems to be related to the basic immunological status of the individual.
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## Abstract Prognosis of stage I melanoma of the skin was evaluated in 747 previously untreated patients observed by the WHO Collaborating Centres for Evaluation of Methods of Diagnosis and Treatment of Melanoma from September 1967 to September 1975. The mean followβup period of these patients was