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Reassessing evidence for a postnatal mitochondrial genetic bottleneck

✍ Scribed by Samuels, David C; Wonnapinij, Passorn; Cree, Lynsey M; Chinnery, Patrick F

Book ID
109916167
Publisher
Nature Publishing Group
Year
2010
Tongue
English
Weight
208 KB
Volume
42
Category
Article
ISSN
1061-4036

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The high prevalence of rare genetic diseases in Finland has been attributed to a founder effect some 2,000 years ago. However, this hypothesis has not been supported from mtDNA sequence and autosomal microsatellite data which indicate high levels of gene diversity. Here we have identified genetic ev