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Reasons for non-prescription of clozapine in treatment-resistant schizophrenia

✍ Scribed by M. Swinton; A.G. Ahmed

Publisher
John Wiley and Sons
Year
1999
Tongue
English
Weight
60 KB
Volume
9
Category
Article
ISSN
0957-9664

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✦ Synopsis

Background Patients in special hospitals who are suffering from schizophrenia have lengthy admissions and this is primarily as a result of poor response to standard neuroleptics. Clozapine has a specific licence for use in such cases yet a significant proportion of special hospital patients have never been exposed to clozapine. Method One third of patients in Ashworth Hospital with schizophrenia or schizoaffective psychosis who had never been prescribed clozapine were assessed using the PANSS and the NOSIE and by interviews.

Results

The main reason for non-prescription of clozapine was the likelihood of poor compliance. Conclusion Measures to increase the compliance of this group of patients could have major benefits.

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