## Abstract The chemistry of the highly substituted cyclobutanone derivative 2, which is easily accessible from 1, is dominated by the steric hindrance caused by the substitutents: Reduction with hydride reagents and nucleophilic additions with methyllithium are less stereoselective than correspond
Rearrangements of 3-heterobicyclo[3.2.0]hept-6-enes
β Scribed by Arthur G. Schultz; Theodore H. Fedynyshyn
- Publisher
- Elsevier Science
- Year
- 1982
- Tongue
- French
- Weight
- 349 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0040-4020
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π SIMILAR VOLUMES
Derivatives of trans-bicyclo[4.1.0]hept-3-ene with chlorine and bromine substituents the 7 position were synthesized and their thermal rearrangements were examined. Thermolysis of the dichloride leads to the formation of the cis-fused isomer, while heating the dibromide results in ring-expanded prod
Thermal deasetation of difluoro-and tetrafluoro-2,3-diasabicyclo[3.2.0lhept-2-enes proceed via two parallel mechanistic pathways, one involving formation of a diradical via simple N2 loss, and the other proceeding via a retro-dipolar cycloadd~on process. A key finding was the absence of isolation of
Single crystal X-ray diffraction analysis of compounds A, B and, C helped us to assign the absolute configurations of the enantiomers of the bicyclo[3.2.0]hept-3-en-6-endo-ols 4-6. These bicyclic alcohols were easily obtained by: (i) stereoselective reductions of the bicyclo[3.2.0]hept-3-en-6-ones 1
The thermal isomerization of 6-difluoromethylenebicyclo[3.2.0]hept-2-ene proceec via two competing 1,3-sigmatropic processes, with an E, nearly identical to that of the hydrocarbon. Sigmatropic isomerizations of the 6-methylenebicyclo[3.2.O]hept-2-ene system have been examined extensively by Hasselm