Rearrangements accompanying the AlCl3-catalysed cyclisation of (1-phenylcyclopropyl)acetyl chloride

✍ Scribed by M.J. Perkins; N.B. Peynircioglu; B.V. Smith

• Book ID: 104224340
• Publisher: Elsevier Science
• Year: 1975
• Tongue: French
• Weight: 109 KB
• Volume: 16
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(00)91204-8

✦ Synopsis

When recently we required the indanone derivative (II), the title reaction seemed to afford a convenient synthetic route. Mild conditions were dictated by the need to avoid the possibility of acid-catalysed scission of the cyclopropaue ring , and we initially followed a procedure which had proved successful' for the cyclisation of 2-phenylcyclopropanecarbonyl chloride. In this, the acid chloride was treated with AX13 in methylene chloride at ~a. 5',