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Rearrangement of Differentially Protected N-Arylhydroxylamines

✍ Scribed by Achim Porzelle; Michael D. Woodrow; Nicholas C. O. Tomkinson


Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
213 KB
Volume
2008
Category
Article
ISSN
1434-193X

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Backbone cyclization has become an important method for generating or stabilizing the bioactive conformation of peptides without affecting the amino acid side-chains. Up to now, backbone cyclic peptides were mostly synthesized with bridges between N-amino- and N-carboxy-functionalized peptide bonds.