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Rearrangement and overexpression of the gene coding for tumor antigen p53 in a rat histiocytoma AK-5

✍ Scribed by Girish Deshpande; A.Leela Kumari; Ashok Khar


Book ID
115923227
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
601 KB
Volume
271
Category
Article
ISSN
0014-5793

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The frequency of point mutations in p53 (exons 4 -7) and in Ki-ras, Ha-ras, and N-ras (exons 1 and 2) and the expression of p53 protein were evaluated in the liver tumors of Wistar rats of a 104week carcinogenicity study on 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone (MX), a chlorine disinf