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Real time studies of the effects of pharmaceutical additives on cell membrane and tight junction permeabilities in CACO-2 cell monolayers

✍ Scribed by Johan Grásjö; Johan Karisson; P. Antursson


Book ID
117628992
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
164 KB
Volume
4
Category
Article
ISSN
0928-0987

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The purpose of this study was to investigate the mechanism of opening of tight junctions in Caco-2 cell monolayers using superporous hydrogel (SPH) and SPH composite (SPHC) polymers as permeation enhancers for peptide drug delivery. Moreover, the transport of octreotide across Caco-2 cell monolayers