Real-time single-heartbeat fast strain-encoded imaging of right ventricular regional function: Normal versus chronic pulmonary hypertension

✍ Scribed by Monda L. Shehata; Tamer A. Basha; Wahid H. Tantawy; Joao A. Lima; Jens Vogel-Claussen; David A. Bluemke; Paul M. Hassoun; Nael F. Osman

• Publisher: John Wiley and Sons
• Year: 2010
• Tongue: English
• Weight: 797 KB
• Volume: 64
• Category: Article
• ISSN: 0740-3194
• DOI: 10.1002/mrm.22408

✦ Synopsis

Abstract

Patients with pulmonary hypertension and suspected right ventricular (RV) dysfunction often have dyspnea at rest, making reliable assessment of RV function using traditional breath‐holding methods difficult to perform. Using single‐heartbeat fast strain encoding (Fast‐SENC) imaging, peak systolic RV circumferential and longitudinal strains were measured in 11 healthy volunteers and 11 pulmonary hypertension patients. Fast‐SENC RV longitudinal strain and circumferential strain measurements were compared to conventional SENC and MR tagging, respectively. Fast‐SENC circumferential and longitudinal RV shortening correlated closely with SENC measurements (r = 0.86, r = 0.90, P < 0.001 for all). Circumferential strain, by conventional tagging, showed moderate correlation with Fast‐SENC in pulmonary hypertension patients only (r = 0.5, P = 0.003). A nonuniform pattern of RV circumferential shortening was depicted in both groups. Peak systolic circumferential strain was significantly reduced at the basal RV in pulmonary hypertension patients (−18.06 ± 3.3 versus −21.9 ± 1.9, P < 0.01) compared to normal individuals, while peak systolic longitudinal strain was significantly reduced at all levels (P < 0.01 for all). Fast‐SENC is a feasible and reliable technique for rapid quantification of RV regional function in a single‐heartbeat acquisition. Information derived from Fast‐SENC allows characterization of RV regional function in normal individuals and in pulmonary hypertension patients. Magn Reson Med, 2010. © 2010 Wiley‐Liss, Inc.