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Real-Time Quantitative Y Chromosome-Specific PCR (QYCS-PCR) for Monitoring Hematopoietic Chimerism after Sex-Mismatched Allogeneic Stem Cell Transplantation

✍ Scribed by Fehse, Boris; Chukhlovin, Alexei; Kuhlcke, Klaus; Marinetz, Olga; Vorwig, Oliver; Renges, Helmut; Kruger, William; Zabelina, Tatyana; Dudina, Olga; Finckenstein, Friedrich Graf

Book ID
111887420
Publisher
Mary Ann Liebert
Year
2001
Tongue
English
Weight
138 KB
Volume
10
Category
Article
ISSN
1061-6128

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## Abstract We compared the results of chimerism analyses with real‐time SNP‐PCR to those obtained by the classical STR‐PCR method in 135 hematopoietic stem cell transplantation recipients. Using 10 different SNP gene loci, the SNP‐PCR method was able to discriminate patient from donor cells in 125