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Real-time PCR detection of multiple lamivudine-resistant mutations with displacing probes in a single tube

โœ Scribed by Huixin Wen; Qingge Li


Book ID
116631136
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
482 KB
Volume
38
Category
Article
ISSN
1386-6532

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## Abstract The UGT1A1 Taqman MGB probe single nucleotide polymorphism (SNP) genotyping assay was developed to detect nucleotide 211 of the UDPโ€glucoronocyltransferase 1A1 (UGT1A1) gene. Defects in this enzyme interfere with process of conjugation of bilirubin and cause unconjugated hyperbilirubine