With increasing protein concentrations, therapeutic protein formulations are increasingly demonstrating significant deviations from ideal dilute solution behavior due to protein-protein interactions. These interactions lead to unique biophysical challenges in the administration of biopharmaceuticals
โฆ LIBER โฆ
Real-time monitoring of the development and stability of biofilms of Streptococcus mutans using the quartz crystal microbalance with dissipation monitoring
โ Scribed by Amy L. Schofield; Timothy R. Rudd; David.S. Martin; David G. Fernig; Clive Edwards
- Book ID
- 108071872
- Publisher
- Elsevier Science
- Year
- 2007
- Tongue
- English
- Weight
- 466 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0956-5663
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Quartz crystal microbalance (QCM) with dissipation can be used to measure the response of the human stratum corneum (SC) attached to the QCM crystal, as it adsorbs or desorbs active ingredients from a liquid medium. The method was demonstrated with the sorption of poly(diallyl dimethyl ammonium chlo