Real-time monitoring of angiotensin II-induced contractile response and cytoskeleton remodeling in individual cells by atomic force microscopy

Observation of angiotensin II-induced ch

Observation of angiotensin II-induced changes in fixed and live mesangial cells by atomic force microscopy

✍ Gi-Ja Lee; Eun-Jin Park; Samjin Choi; Jeong-Hoon Park; Kyung-Hwan Jeong; Kyung-S 📂 Article 📅 2010 🏛 Elsevier Science 🌐 English ⚖ 752 KB

Glomerular mesangial cells (MCs) are centrally located in the glomerulus. MCs control not only glomerular filtration, but also the response to local injury, including cell proliferation and basement membrane remodeling. Angiotensin II (Ang II) plays an important role in kidney function regulation, a