Real-time and computerized sonographic scoring system for predicting malignant cervical lymphadenopathy
✍ Scribed by Li-Jen Liao; Chi-Te Wang; Yi-Ho Young; Po-Wen Cheng
- Book ID
- 102233229
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 104 KB
- Volume
- 32
- Category
- Article
- ISSN
- 1043-3074
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✦ Synopsis
Abstract
Background.
To identify malignant cervical lymphadenopathy, we established a real‐time, computerized scoring system based on sonographic findings and demographic data.
Methods.
One hundred eight patients with neck lymphadenopathy, receiving ultrasonography and ultrasound‐guided fine‐needle aspiration (US‐FNA), were used to construct a predictive model. This model was validated by another independent patient cohort.
Results.
A predictive scoring scale was proposed by multivariate logistic regression analysis: 0.06 × (age) + 4.76 × (S/L ratio) + 2.15 × (internal echo) + 1.80 × (vascular pattern). Cervical lymphadenopathy was regarded as malignant with a score ≥7. The formula was programmed into a synchronized, computerized sonographic reporting system. Prospective validation of this predictive tool showed excellent sensitivity (100%), specificity (88.0%), and overall accuracy (90.1%).
Conclusion.
A real‐time and practical sonographic scoring system was built and validated to provide the physician prompt and reliable probability guidance for performing US‐FNA cytology in managing cervical lymphadenopathy. © 2009 Wiley Periodicals, Inc. Head Neck, 2010