Reagent-Free Nazarov Cyclizations.
β Scribed by Frederic Douelle; Lauren Tal; Michael F. Greaney
- Book ID
- 101979172
- Publisher
- John Wiley and Sons
- Year
- 2005
- Weight
- 21 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0931-7597
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Tri-and tetrasubstimted 1,4-dien-3-oues 1 were treated with Lewis acid in the presence of tdethylsilane, furnishing either silyl euol ethers 4 or cyclopentanunes 5 in goud yields, depending upon wt~k-up conditions. This reaction is l~resumed to occur through oxyallyl intea'mndiate 3, which undergoes
Benzamides with tethered acetal groups undergo reactions in CF(3)SO(3)H to give ring-fused isoindolinones by a cyclization cascade. The reaction initially forms an N-acyliminium ion which then gives the isoindolinone by the aza-Nazarov reaction. An unusual variant also cyclizes at the allylic positi
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