Readings in Advanced Pharmacokinetics - Theory, Methods and Applications

✍ Scribed by Noreddin A. (Ed.)

• Tongue: English
• Leaves: 388
• Category: Library

✦ Synopsis

InTech, 2012. - 388 p. - This book covers up to date information and practical topics related to the study of drug pharmacokinetics in humans and in animals. The book is designed to offer scientists, clinicians and researchers a choice to logically build their knowledge in pharmacokinetics from basic concepts to advanced applications. This book is organized into two sections. The first section discusses advanced theories that include a wide range of topics; from bioequivalence studies, pharmacogenomics in relation to pharmacokinetics, computer based simulation concepts to drug interactions of herbal medicines and veterinary pharmacokinetics. The second section advances theory to practice offering several examples of methods and applications in advanced pharmacokinetics.
Contents
Advanced Concepts
Bioequivalence Studies
Computer Simulations as a Tool for Optimizing Bioequivalence Trials
Evaluation of Percutaneous Drug Permeation Using a Lateral Sectioning Approach
Pharmacogenomics Dictate Pharmacokinetics: Polymorphisms in Drug-Metabolizing Enzymes and Drug-Transporters
Genetic Variation in Drug Disposition
Application of Pharmacokinetics/Pharmacodynamics (PK/PD) in Designing Effective Antibiotic Treatment Regimens
Pharmacokinetics and Drug Interactions of Herbal Medicines: A Missing Critical Step in the Phytomedicine/Drug Development Process
Pharmacokinetics of Antimicrobials in Food Producing Animals
Comparative Veterinary Pharmacokinetics
Methods and Applications
Observer-Based Strategies for Anesthesia Drug Concentration Estimation
Optimal Pharmacokinetics of Cyclosporine and Tacrolimus Based Relationship Among AUC, Trough and Peak Concentration
Pharmacokinetics and Metabolized Caroteniods in Liver of Single Dose Administration in Fancy Carp (Cyprinus carpio)
Correlation of in vitro Dissolution Profiles with in vivo Pharmacokinetic Parameters of Some Commercial Brands of Aspirin Tablets Marketed in Nigeria
Bioavailability of Citrus Polymethoxylated Flavones and Their Biological Role in Metabolic Syndrome and Hyperlipidemia
Role of Aldehyde Oxidase and Xanthine Oxidase in the Metabolism of Purine-Related Drugs
Pharmacokinetic/Pharmacodynamic (PK/PD) Modeling of Anti-Neoplastic Agents
Pharmacokinetic (PK) and Pharmacodynamic Profiles of Artemisinin Derivatives Influence Drug Neurotoxicity in Animals
One Step Closer to the Target: Intracellular Pharmacokinetics of Gemcitabine

✦ Subjects

Медицинские дисциплины;Фармакология;Общая и частная фармакология