Reactivity of the Pyrimidine Nitrogen Atom toward an Acetal Moiety: Formation of 3-Ethoxy-2,3-dihydroimidazo[1,2-c]pyrimidines by Intramolecular Cyclization of N-(2,2-Diethoxyethyl)pyrimidine-4-amines

5,7-Diacetyl-13-benzyl-7,8-dihydro-5H,8a

5,7-Diacetyl-13-benzyl-7,8-dihydro-5H,8aH,13H-diindolo[2,3-c;2,3-d]pyrimidin-8-yl acetate, the result of an intramolecular cycloaddition between an N-benzylindole and a 1,2,4,5-tetrazine

✍ Helliwell, Madeleine ;Corden, Steven ;Joule, John A. 📂 Article 📅 2007 🏛 International Union of Crystallography 🌐 English ⚖ 339 KB

An intramolecular Diels-Alder-type cycloaddition between an indole and a 1,2,4,5-tetrazine produced the title compound, C 29 H 26 N 4 O 4 , the first example of a pentaheterocyclic structure obtained via loss of nitrogen and addition of the elements of acetic anhydride. Of the four N atoms in the mo

Reactivity of the Pyrimidine Nitrogen Atom toward an Acetal Moiety: Formation­ of 3-Ethoxy-2,3-dihydroimidazo[1,2-c]pyrimidines by Intramolecular Cyclization of N-(2,2-Diethoxyethyl)pyrimidine-4-amines

Reactivity of the Pyrimidine Nitrogen Atom toward an Acetal Moiety: Formation of 3-Ethoxy-2,3-dihydroimidazo[1,2-c]pyrimidines by Intramolecular Cyclization of N-(2,2-Diethoxyethyl)pyrimidine-4-amines