## Abstract We report the reactivity of a novel murine IgM monoclonal antibody (MAb), 3H‐1, in formalin‐fixed tissue from a series of 44 patients with squamous‐cell cancers (SCCs) of the upper aerodigestive tract. The antigen detected by 3H‐1 MAb is not expressed in simple squamous epithelia and on
Reactivity of monoclonal antibodies leu 1 and OKT1 with malignant human lymphoid cells. Correlation with conventional cell markers
✍ Scribed by Daniel M. Knowles II; James P. Halper; Walid Azzo; Chang Yl Wang
- Publisher
- John Wiley and Sons
- Year
- 1983
- Tongue
- English
- Weight
- 877 KB
- Volume
- 52
- Category
- Article
- ISSN
- 0008-543X
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Immunization of mice with membranes from a virus‐transformed human keratinocyte cell line (KJD‐I/SV40) yielded an IgM monoclonal antibody (MAb 3H‐1) which reacted with the membrane and cytoplasm of KJD‐I/SV40 cells and in the perinuclear region of a squamous‐cell carcinoma line (Colo‐16
Although its precise function has not yet been established, galectin-1 seems to play a role in tumor progression. In this study, we investigated galectin-1 mRNA expression in human glioma specimens and glioma cell lines. Northern blot analysis showed higher galectin-1 mRNA levels in glioma tissues.
While human malignant mesothelioma is extremely resistant to chemotherapy, its intrinsic resistance mechanisms remain largely unknown. In this study, we used normal human mesothelial cells and 5 human mesothelioma cell lines not previously exposed to chemotherapeutic agents to demonstrate that the m