𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Reactivity of 3-amino-3H-quinazolin-4-one derivatives towards some electrophilic and nucleophilic reagents and using of the products in the building of some interesting heterocycles as anticancer agent

✍ Scribed by Taha.M. Abdel-Rahman

Publisher
Journal of Heterocyclic Chemistry
Year
2006
Tongue
English
Weight
424 KB
Volume
43
Category
Article
ISSN
0022-152X

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

magnified image

The chemical reactivity of N‐[1‐(3‐amino‐6,8‐dibromo‐4‐oxo‐3,4‐dihydro‐quinazolin‐2‐yl)‐2‐(2‐chlorophenyl)‐vinyl]benzamide (3) towards electrophilic and nucleophilic reagents have been reported. Structures of the products 3‐24 have been confirmed by elemental analysis and spectral data (IR, ^1^H‐NMR, ^13^C and MS). The bioassay indicates that some of the prepared compounds have a good selective anticancer activity.

📜 SIMILAR VOLUMES

Reactivity of 3-Amino-3H-quinazolin-4-on
Reactivity of 3-Amino-3H-quinazolin-4-one Derivatives Towards Some Electrophilic and Nucleophilic Reagents and Using of the Products in the Building of Some Interesting Heterocycles as Anticancer Agent.
✍ Taha. M. Abdel-Rahman 📂 Article 📅 2006 🏛 John Wiley and Sons ⚖ 23 KB 👁 2 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.