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Reactivity of 2-Substituted Imidazo[1,2-b]pyridazines: Preparation of 3-Nitro-, Nitroso and Chloro Derivatives.

✍ Scribed by Maud Hervet; Christophe Galtier; Cecile Enguehard; Alain Gueiffier; Jean-Claude Debouzy


Publisher
John Wiley and Sons
Year
2010
Weight
32 KB
Volume
33
Category
Article
ISSN
0931-7597

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Reactivity of 2-substituted imidazo[1,2-
✍ Maud Hervet; Christophe Galtier; CÉcile Enguehard; Alain Gueiffier; Jean-Claude 📂 Article 📅 2002 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 56 KB

## Abstract The synthesis of 2‐substitutedimidazo[1,2‐__b__]pyridazines and their reactivity towards electrophilic substitutions are reported. The nitration was shown to be very dependent on the nature of the 2 substituent. Nitrosation using sodium nitrite in acetic acid media as a general method f