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Reactivity of 2-methylene-1,3-dicarbonyl compounds. 1,3-dipolar cycloaddition reaction with nitrile oxide

✍ Scribed by Masashige Yamauchi


Publisher
Journal of Heterocyclic Chemistry
Year
2002
Tongue
English
Weight
58 KB
Volume
39
Category
Article
ISSN
0022-152X

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✦ Synopsis


Abstract

The reaction of 2‐methylene‐1,3‐dicarbonyl compounds 1 and nitrile oxides, which were prepared from hydroxymoyl chlorides 2 with triethylamine, gave 5,5‐disubstituted 2‐isoxazolines 3 regioselectively.


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1,3-dipolar cycloaddition reactions of n
✍ Li Tian; Guo-Yan Xu; Yong Ye; Lun-Zu Liu πŸ“‚ Article πŸ“… 2003 πŸ› Journal of Heterocyclic Chemistry 🌐 English βš– 91 KB

## Abstract The reaction of prop‐1‐ene‐1,3‐sultone **1** with a variety of nitrile oxides **3** afforded novel [3+2] cycloaddition products **4** in good yield. The cycloaddition reaction achieved excellent regioselectivity.