Reactivity indices of adamantane-containing diamines in the synthesis of polyimides
✍ Scribed by I. A. Novakov; B. S. Orlinson; O. A. Kuznechikov; I. O. Kulago; A. I. Pavlyuchko; Z. M. Sabirov; V. N. Urazbaev; Yu. B. Monakov
- Book ID
- 105595202
- Publisher
- Springer
- Year
- 1999
- Tongue
- English
- Weight
- 206 KB
- Volume
- 48
- Category
- Article
- ISSN
- 1573-9171
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## Abstract A new diacetamido‐diamine monomer, __N__′‐[7‐(acetyl‐4‐aminoanilino)‐9,9‐dioctylflouren‐2‐yl]‐__N__′‐4‐aminophenyl) acetamide (ADOAc), with flourene‐based structure was prepared from the reaction of 4‐aminoacetanillide with 2,7‐dibromo‐9,9‐dioctylfluorene in the presence of 10 mol % CuI
2-adamantanole was the protecting group of the aspartate 13-COOH moiety during the peptide synthesis and survived the final peptide cleavage and deprotection carried out under controlled conditions. MEN 10586 showed an agonist activity comparable to that of the parent compound MEN 10210 at NK~ and N