Reactivity and mechanisms of metalloporphyrin- catalyzed oxidations

✍ Scribed by John T. Groves

• Publisher: John Wiley and Sons
• Year: 2000
• Tongue: English
• Weight: 50 KB
• Volume: 04
• Category: Article
• ISSN: 1088-4246
• DOI: 10.1002/(sici)1099-1409(200006/07)4:4<350::aid-jpp249>3.0.co;2-g

✦ Synopsis

Effective systems for the catalytic oxygenation of hydrocarbons have been developed based on metalloporphyrins containing iron, manganese and ruthenium. These metalloporphyrin catalysts were inspired by studies of the mechanism of the heme oxygenase cytochrome P450 and related enzymes. Oxometalloporphyrins, which have now been spectroscopically characterized, have very high reactivity as oxygen transfer agents. A combination of experimental and computational methods has begun to provide an understanding of the structure and reactivity of these oxometalloporphyrin complexes and the mechanisms of oxygen transfer reactions they catalyze.