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Reactive oxygen species modulate Zn2+-induced apoptosis in cancer cells

✍ Scribed by Mauro Provinciali; Alessia Donnini; Katy Argentati; Grazia Di Stasio; Beatrice Bartozzi; Giovanni Bernardini

Book ID
114275029
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
915 KB
Volume
32
Category
Article
ISSN
0891-5849

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## Abstract There is an emerging evidence that plumbagin (5‐hydroxy‐2‐methyl‐1, 4‐naphthoquinone) may have potential as a chemotherapeutic agent. However, the growth inhibitory mechanisms of plumbagin have remained unexplored. The aim of the study was to determine whether plumbagin‐induced cell dea