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Reactive oxygen species involved in sulforaphane-induced STAT3 inactivation and apoptosis in DU145 prostate cancer cells

โœ Scribed by Wonil Koh; Kwang Seok Ahn; Soo-Jin Jeong; Hyo-Jung Lee; Minseok Kim; Hyo-Jeong Lee; Eun-Ok Lee; Sung-Hoon Kim


Book ID
107372321
Publisher
Springer
Year
2010
Tongue
English
Weight
939 KB
Volume
55
Category
Article
ISSN
1001-6538

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โœ Yen-Chou Chen; Shoei-Yn Lin-Shiau; Jen-Kun Lin ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 315 KB ๐Ÿ‘ 2 views

Recent studies indicate that arsenic may generate reactive oxygen species to exert its toxicity. However, the mechanism is still unclear. In this study, we demonstrate that arsenite is able to induce apoptosis in a concentration-and time-dependent manner; however, arsenate is unable to do so. An inc