The bacterial alkaloid staurosporine is widely employed as an inducer of apoptosis in many cell types including neurons. The intracellular cascades that mediate staurosporine-induced apoptosis are largely unknown. Exposure of cultured PC12 cells to staurosporine resulted in a rapid (min) and prolong
Reactive oxygen species induced by proteasome inhibition in neuronal cells mediate mitochondrial dysfunction and a caspase-independent cell death
β Scribed by Luena Papa; Evan Gomes; Patricia Rockwell
- Publisher
- Springer
- Year
- 2007
- Tongue
- English
- Weight
- 799 KB
- Volume
- 12
- Category
- Article
- ISSN
- 1360-8185
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