Reactivation of the maternally imprinted IGF2 allele in TGFα induced hepatocellular carcinomas in mice

Alterations of the M6p/Igf2 receptor gen

Alterations of the M6p/Igf2 receptor gene in hepatocellular carcinomas induced by N-nitrosodiethylamine and a choline-deficient L-amino acid–defined diet in rats

✍ Toshifumi Tsujiuchi; Yasutaka Sasaki; Yasuo Oka; Hiroki Kuniyasu; Yoichi Konishi 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 197 KB

## Abstract To elucidate whether the M6p/Igf2 receptor (M6p/Igf2r) gene might be involved in exogenous and endogenous liver carcinogenesis, we investigated its alteration in hepatocellular carcinomas (HCCs) induced by __N__‐nitrosodiethylamine (DEN) and by a choline‐deficient L‐amino acid‐defined (