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Reactivation of death receptor 4 (DR4) expression sensitizes medulloblastoma cell lines to TRAIL

✍ Scribed by Dolly G. Aguilera; Chandra M. Das; Neeta D. Sinnappah-Kang; Celine Joyce; Pete H. Taylor; Sijin Wen; Martin Hasselblatt; Werner Paulus; Greg Fuller; Johannes E. Wolff; Vidya Gopalakrishnan


Book ID
106481185
Publisher
Springer US
Year
2009
Tongue
English
Weight
747 KB
Volume
93
Category
Article
ISSN
0167-594X

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✍ Yifan Min; Juan Shi; Yaxi Zhang; Shilian Liu; Yanxin Liu; Dexian Zheng πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 205 KB

## Abstract In the present study we demonstrated Jurkat leukemia cell lines of TIB152 and TIB153 with different sensitivities to recombinant soluble TRAIL cytotoxicity. TRAIL receptor death receptor 5 (DR5) was constitutively localized in the rafts in both cell lines. FADD, caspase‐8, and PI3K‐p85