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Reactions with α-substituted cinnamonitriles. A novel synthesis of hexa-substituted pyridines

✍ Scribed by Hamdy A. Hammouda; Ahmed; M. El-Reedy; Sohair M. Hussain


Book ID
112128316
Publisher
Journal of Heterocyclic Chemistry
Year
1986
Tongue
English
Weight
278 KB
Volume
23
Category
Article
ISSN
0022-152X

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Vilsmeier–Haack reactions of α-hydroxyke
✍ Ajith Dain Thomas; C.V Asokan 📂 Article 📅 2002 🏛 Elsevier Science 🌐 French ⚖ 57 KB

The reaction of a-hydroxyketenedithioacetals, generated by the 1,2-addition of methyl Grignard reagent to aoxoketenedithioacetals, with the Vilsmeier reagent was investigated. The reaction proceeds with acid-catalysed dehydration to afford sulphur substituted 1,3-butadienes, which undergo subsequent